GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
| Institute |
|---|
| Versiti Blood Research Institute |
| Cat. #: | 155086 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Target: | Glycoprotein 1B |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | GPIb |
|---|---|
| Product description: | GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 75 kDa |
| Immunogen: | gpIb |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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