Cat. #151897
Anti-FOXP2 [73A/8]
Cat. #: 151897
Sub-type: Primary antibody
Unit size: 100 ug
Target: FOXP2
Class: Monoclonal
Application: IHC ; WB ; ChIP
Reactivity: Human ; Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Alison Banham
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-FOXP2 [73A/8]
- Clone: 73A/8
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human ; Mouse
- Application: IHC ; WB ; ChIP
- Description: The FOXP2-73A/8 antibody detects human and murine FOXP2 and does not cross-react with other members of the FOXP family (FOXP1, FOXP3 or FOXP4).
- Immunogen: Bacterially expressed GST-protein containing N-terminus of FOXP2
- Isotype: IgG1
- Myeloma used: P3X63Ag8.653
Target Details
- Target: FOXP2
- Target background: FOXP2 is a member of the forkhead transcription factor. Its mutation is associated with an inherited speech and language disorder and its biological roles have primarily been studied in neuronal tissues. FOXP2 is also aberrantly expressed in abnormal plasma cells and it may play a role in the pathogenesis of multiple myeloma.
Applications
- Application: IHC ; WB ; ChIP
Handling
- Format: Liquid
- Concentration: 1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: '-15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.
- Wong et al. 2016. Oncotarget. :. PMID: 27224915.
- Gascoyne et al. 2015. PLoS One. 10(6):e0128513. PMID: 26034982.
- The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.
- Campbell et al. 2010. Br J Haematol. 149(2):221-30. PMID: 20096010.
- Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.
