Anti-Fibrinogen-like Protein 1 [177 m01]

FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.

Contributors

Inventor Institute
Leiping Chen Yale University
Cat. #: 159684
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology
Application: ELISA
Target: Fibrinogen-like Protein 1
Reactivity: Human
Host: Mouse
Class: Monoclonal
Alternate name: FGL-1
Product description: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Target background: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Wang et al. 2019. Cell. 176(1-2):334-347.e12. PMID: 30580966.

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