#151359

Anti-FCGR2 [KB61]

Cat. #151359

Anti-FCGR2 [KB61]

Cat. #: 151359

Unit size: 100 ug

Availability: 3-4 weeks

Target: Fc gamma Recptor II (FCGR2, CD32)

Class: Monoclonal

Application: FACS ; IHC; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Karen Pulford

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-FCGR2 [KB61]
  • Alternate name: Fc Fragment Of IgG Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2; FCG2; CD32; FCGR2; CD32B
  • Research fields: Immunology;Stem cell biology
  • Clone: KB61
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC; IP
  • Description: Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.
  • Immunogen: Hairy cell leukaemia cells
  • Isotype: IgG1 kappa
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Fc gamma Recptor II (FCGR2, CD32)
  • Target background: Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.

Applications

  • Application: FACS ; IHC; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Greenman J et al. 1991. Mol Immunol 28:1243-54. PMID: 1835758 Pulford K et al. 1986. Immunology 57:71-6. PMID: 3484721 Matsumoto K et al, J Immunol. 2004 Feb 15
  • 172(4):2186-93. PMID: 14764685