Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin.
| Inventor | Institute |
|---|---|
| Gijs Johannes de Jongh | Radboud University Medical Center |
| Cat. #: | 160399 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Tissue-specific biology |
| Application: | Fn |
| Target: | Elafin; SKALP |
| Host: | Rabbit |
| Class: | Polyclonal |
| Alternate name: | Elastase-specific inhibitor (ESI), Peptidase inhibitor 3 (PI-3), Protease inhibitor WAP3,Skin-derived antileukoproteinase (SKALP), WAP four-disulfide core domain protein 14 |
|---|---|
| Product description: | Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin. |
| Conjugation: | Unconjugated |
| Molecular weight: | 18kDa |
| Immunogen: | P19957 |
| Immunogen Uniprot ID: | P19957 |
| Target background: | Some anti-elastase activity is found in cultured keratinocytes and in epidermis from psoriasis patients, but not in normal human epidermis. This inhibitory effect has been shown to be mediated by SKALP, Skin-derived antileukoproteinase also known as Elafin. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Schalkwijk et al. 1991. Biochim Biophys Acta. 1096(2):148-54. PMID: 2001428. |
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