#153387

Anti-EGFR [ICR11]

Cat. #153387

Anti-EGFR [ICR11]

Cat. #: 153387

Sub-type: Primary antibody

Unit size: 100 ug

Target: EGFR

Class: Monoclonal

Application: FACS ; IHC ; IP

Reactivity: Human

Host: Rat

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Chris Dean

Institute: The Institute of Cancer Research

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-EGFR [ICR11]
  • Alternate name: ERBB1; HER1; epidermal growth factor receptor; ERBB; mENA; PIG61
  • Research fields: Cancer;Cell signaling and signal transduction
  • Clone: ICR11
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 42.4 kDa
  • Reactivity: Human
  • Host: Rat
  • Application: FACS ; IHC ; IP
  • Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
  • Immunogen: Squamous cell carcinoma
  • Isotype: IgG2a

Target Details

  • Target: EGFR
  • Molecular weight: 42.4 kDa
  • Target background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Applications

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C