DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes.
| Inventor | Institute |
|---|---|
| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151239 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | FACS ; IHC ; IF ; IP ; WB |
| Target: | DMC1 |
| Reactivity: | Bovine ; Human ; Mouse |
| Clone: | 2H12/4 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Disrupted meiotic cDNA 1 homolog, Disrupted meiotic cDNA 1, yeast homolog of, dJ199H16.1, DMC 1, DMC1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast), DMC1 homologue |
|---|---|
| Product description: | DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | human DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pelet) |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Lin et al. 2013. PLoS Genet. 9(5):e1003516. PMID: 23717213. Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression. Erenpreisa et al. 2009. Exp Cell Res. 315(15):2593-603. PMID: 19463812. The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells. Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151030 | Anti-Progesterone [11P14] |
Key Info
Anti-Progesterone [11P14]
|
View Tool | |||||||||||||||||||
| 151015 | Anti-CyclinA [E70.1] |
Key Info
Anti-CyclinA [E70.1]
|
View Tool | |||||||||||||||||||
| 151025 | Anti-Vascular endothelium [10] |
Key Info
Anti-Vascular endothelium [10]
|
View Tool | |||||||||||||||||||
| 151033 | Anti-HSVUL42 [13C9] |
Key Info
Anti-HSVUL42 [13C9]
|
View Tool | |||||||||||||||||||
| 151037 | Anti-Cdk1 [17 (A17)] |
Key Info
Anti-Cdk1 [17 (A17)]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.