Anti-Cytochrome P450 8B1 [M15-P3B7]

Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
Cat. #: 152155
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
Application: ELISA ; IHC ; WB
Target: Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
Reactivity: Human ; Rat
Clone: M15-P3B7
Host: Mouse
Class: Monoclonal
Product description: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Peptide sequence QPSHDVRFR (amino acids 486 494)
Myeloma used: P3X63Ag8.653
Target background: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Swan et al. 2016. Oncotarget. :. PMID: 27341022.

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