Cat. #152155
Anti-Cytochrome P450 8B1 [M15-P3B7]
Cat. #: 152155
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 8B1 [M15-P3B7]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: M15-P3B7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human ; Rat
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
- Immunogen: Peptide sequence QPSHDVRFR (amino acids 486 494)
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
Target Details
- Target: Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
- Tissue cell line specificity: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
- Target background: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- Swan et al. 2016. Oncotarget. :. PMID: 27341022.
