Cat. #152123
Anti-Cytochrome P450 51A1 [N6-P2H5*G8]
Cat. #: 152123
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: CYP51A1- Cytochrome P450, family 51, subfamily A, polypeptide 1.
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 51A1 [N6-P2H5*G8]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: N6-P2H5*G8
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP51A1 is an endoplasmic reticulum protein that participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.
- Immunogen: Ovalbumin-conjugated synthetic peptide NPVIRYKRRS (C-terminal sequence).
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: WB: pooled human liver microsomes
Target Details
- Target: CYP51A1- Cytochrome P450, family 51, subfamily A, polypeptide 1.
- Tissue cell line specificity: WB: pooled human liver microsomes
- Target background: Cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP51A1 is an endoplasmic reticulum protein that participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- Swan et al. 2016. Oncotarget. :. PMID: 27341022.
