Cat. #151141
Anti-Cytochrome P450 3A1 [P6]
Cat. #: 151141
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Cytochrome P450 3A1, CYP3A1
Class: Monoclonal
Application: ELISA ; FACS ; WB
Reactivity: Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roland Wolf
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 3A1 [P6]
- Research fields: Cancer;Tissue-specific biology;Cell signaling and signal transduction;Metabolism
- Clone: P6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 150-160 kDa
- Reactivity: Human ; Mouse ; Rat
- Host: Mouse
- Application: ELISA ; FACS ; WB
- Description: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
- Immunogen: Rat liver cytochrome P450 3A1
- Immunogen uniprot id: P06756
- Isotype: IgG1
- Recommended controls: A375M melanoma
Target Details
- Target: Cytochrome P450 3A1, CYP3A1
- Molecular weight: 150-160 kDa
- Target background: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
Applications
- Application: ELISA ; FACS ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Probert et al. 2014. Toxicol Sci. 137(2):350-70. PMID: 24235770.
- Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies.
- Hu et al. 2011. Drug Metab Dispos. 39(3):419-25. PMID: 21135265.
- Opposite effect of diabetes mellitus induced by streptozotocin on oral and intravenous pharmacokinetics of verapamil in rats.
- Matuskova et al. 2009. Neuro Endocrinol Lett. 30 Suppl 1:41-5. PMID: 20027143.
- Influence of probiotics on rat liver biotransformation enzymes.
