Cat. #153385
Anti-cMyc [JAC6]
Cat. #: 153385
Sub-type: Primary antibody
Unit size: 100 ug
Target: myc
Class: Monoclonal
Application: IHC ; IF ; IP ; WB
Reactivity: Human
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Richard Marais
Institute: The Institute of Cancer Research
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-cMyc [JAC6]
- Alternate name: Myc proto oncogene protein; c Myc
- Cancer: Breast cancer;Gynaecologic cancer;Lung cancer
- Cancers detailed: Breast cancer;Broadly Applicable;Cervix;Colorectal;Lung;Stomach
- Research fields: Apoptosis and autophagy;Cancer;Cell biology;Immunology
- Clone: JAC6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 53 kDa
- Reactivity: Human
- Host: Rat
- Application: IHC ; IF ; IP ; WB
- Description: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
- Immunogen: Synthetic peptide, corresponding to amino acids 408-439 of Human c-Myc
- Isotype: IgG1
Target Details
- Target: myc
- Molecular weight: 53 kDa
- Target background: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
Applications
- Application: IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Su et al. 2015. J Cell Sci. 128(22):4063-73. PMID: 26430213.
- Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site.
- von Philipsborn et al. 2014. Curr Biol. 24(3):242-51. PMID: 24440391.
- Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.
- Coleman et al. 2011. J Biol Chem. 286(19):17205-16. PMID: 21454556.
- Critical role of the beta-subunit CDC50A in the stable expression, assembly, s...