#151707

Anti-CLEC9A [8F9]

Cat. #151707

Anti-CLEC9A [8F9]

Cat. #: 151707

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Human DNGR1

Class: Monoclonal

Application: FACS ; IHC ; FACS ; IF

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CLEC9A [8F9]
  • Research fields: Immunology;Stem cell biology
  • Clone: 8F9
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; FACS ; IF
  • Description: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
  • Immunogen: RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Mouse IgG2a isotype-matched control mAbs

Target Details

  • Target: Human DNGR1
  • Tissue cell line specificity: Mouse IgG2a isotype-matched control mAbs
  • Target background: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.

Applications

  • Application: FACS ; IHC ; FACS ; IF

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Poulin et al. 2010. J Exp Med. 207:1261-71. [PMID: 20479117]
  • Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]
  • Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]
  • Canavan et al. 2018. JCI Insight. 3(23):. PMID: 30518680.