Anti-CD56 [123C3]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-CD56 [123C3]
• Alternate name: NCAM1; Neural Cell Adhesion Molecule 1
• Research fields: Cell biology;Neurobiology
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 140 kDa
• Reactivity: Human
• Host: Mouse
• Application: IHC ; IF ; IP
• Description: CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (Î?δ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. CD56 has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
• Immunogen: Human small cell lung cancer membrane fraction
• Isotype: IgG1

Target Details

• Target: CD56
• Molecular weight: 140 kDa
• Target background: CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (?d) cells and activated CD8+ T cells, as well as on dendritic cells. CD56 has been implicated as having a role in cellcell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.

Applications

• Application: IHC ; IF ; IP

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Kibbelaar et al. 1991. Eur J Cancer. 27(4):431-5. PMID: 1851619.
• Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.
• Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003.