This antibody recognizes the murine lymphocyte antigen MALA-2.
| Inventor | Institute |
|---|---|
| Fumio Takei | BC Cancer |
| Cat. #: | 160510 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology |
| Application: | IP ; FACS ; WB |
| Target: | CD54 |
| Reactivity: | Mouse |
| Host: | Rat |
| Class: | Monoclonal |
| Alternate name: | ICAM-1 |
|---|---|
| Product description: | CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b kappa |
| Molecular weight: | 95 kDa |
| Immunogen: | NS-1 cells |
| Myeloma used: | Y3 |
| Target background: | CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Horley et al. 1989. EMBO J. 8(10):2889-96. PMID: 2573511. Takei et al. 1985. J Immunol. 134(3):1403-7. PMID: 2981916. |
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