Cat. #154730
Anti-CD49F (Integrin Alpha 6) [GoH3]
Cat. #: 154730
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD49F
Class: Monoclonal
Application: FACS ; IHC ; IP
Reactivity: Dog ; Human ; Mouse
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Arnoud Sonnenberg
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD49F (Integrin Alpha 6) [GoH3]
- Alternate name: ITGA6
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 126 kDa
- Strain: Balb/c
- Reactivity: Dog ; Human ; Mouse
- Host: Rat
- Application: FACS ; IHC ; IP
- Description: The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Specific loss of this integrin chain in the intestinal epithelium, and thus of their hemidesmosomes, induces long-standing colitis and infiltrating adenocarcinomas.
- Immunogen: 1242-1255 of the C-terminus of the Human c-erbB-2/HER-2/neu protein. This sequence is identical in Rat neu
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: CD49F
- Molecular weight: 126 kDa
- Target background: The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Specific loss of this integrin chain in the intestinal epithelium, and thus of their hemidesmosomes, induces long-standing colitis and infiltrating adenocarcinomas.
Applications
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Yoshino et al. 2000. Exp Anim. 49(2):97-110. PMID: 10889948.
- Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies.
- Galkowska et al. 1996. Vet Immunol Immunopathol. 53(3-4):329-34. PMID: 8969052.
- Ticchioni et al. 1995. J Immunol. 154(3):1207-15. PMID: 7529794.
