Cat. #153222
Anti-CD44 [BU75]
Cat. #: 153222
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD44
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Margaret Goodall
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD44 [BU75]
- Alternate name: HCAM; homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; Hermes antigen; lymphocyte homing receptor; ECM-III; HUTCH-1.
- Research fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology
- Clone: BU75
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 90-95 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; WB
- Description: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
- Immunogen: Folicual dentritic cells and germinal centre B cells
- Isotype: IgG2a
- Recommended controls: Human tonsil tissue, HL-60 whole cell lysate, HeLa whole cell lysate
Target Details
- Target: CD44
- Molecular weight: 90-95 kDa
- Tissue cell line specificity: Human tonsil tissue, HL-60 whole cell lysate, HeLa whole cell lysate
- Target background: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Applications
- Application: FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.
- Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
- Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.
