Cat. #155246
Anti-CD3 [500.A2]
Cat. #: 155246
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD3
Class: Monoclonal
Host: Hamster
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Yale University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD3 [500.A2]
- Cancer: Head and neck cancer
- Cancers detailed: Nasopharyngeal
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Host: Hamster
- Description: Monoclonal antibody capable of activating T cells and cloned T cell lines. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3? and 2X CD3?), associates with the T cell antigen receptor (TCR. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present ...
- Immunogen: 25-kDa e chain of the T-cell receptor-associated CD3 complex
- Immunogen uniprot id: A0A3Q0CNZ4
- Isotype: IgG
Target Details
- Target: CD3
- Target background: Monoclonal antibody capable of activating T cells and cloned T cell lines. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3d and 2X CD3), associates with the T cell antigen receptor (TCR. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is p...
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
References
- Chen et al. 2019. JCI Insight. 4(22):. PMID: 31723059.
- Trittel et al. 2019. Sci Rep. 9(1):16362. PMID: 31704965.
- Czarnewski et al. 2019. Nat Commun. 10(1):2892. PMID: 31253778.
- Zwick et al. 2019. Front Immunol. 10:222. PMID: 30809231.
- Shahbaz et al. 2018. PLoS Biol. 16(12):e2006649. PMID: 30550561.
- Maj et al. 2017. Nat Immunol. 18(12):1332-1341. PMID: 29083399.
- Long et al. 2016. Genes (Basel). 8(1):. PMID: 28035981.
- Portoles et al. 1989. J Immunol. 142(12):4169-75. PMID: 2470817.
