CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151353 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Immunology;Stem cell biology |
| Application: | FACS ; IHC |
| Target: | CD20 |
| Reactivity: | Human |
| Clone: | PDR78 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1; Leukocyte Surface Antigen Leu-16; CD2 Antigen; CD2; Bp35; B-Lymphocyte Cell-Surface Antigen B1 |
|---|---|
| Product description: | CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues. |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Immunogen: | Pokeweed mitogen-activated Burkitt's lymphoma cell lines. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137. |
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