#151094

Anti-Casein [F20.14]

Cat. #151094

Anti-Casein [F20.14]

Cat. #: 151094

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Casein beta subunit

Class: Monoclonal

Application: IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Joy Burchell ; Joyce Taylor-Papadimitriou

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Casein [F20.14]
  • Research fields: Cell biology
  • Clone: F20.14
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 28 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; WB
  • Description: F20.14 can be used as in vitro markers of terminally differentiated breast lumenal epithelial cells.
  • Immunogen: Purified casein and a-lactalbumin.
  • Isotype: IgG1
  • Myeloma used: P3X63Ag8.653

Target Details

  • Target: Casein beta subunit
  • Molecular weight: 28 kDa
  • Target background: Caseins are the major proteins found in milk.

Applications

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.88 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Bonuccelli et al. 2012. Cell Cycle. 11(21):3972-82. PMID: 23047602.
  • The milk protein a-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis.
  • Burchell et al. 1985. Hybridoma. 4(4):341-50. PMID: 3905581.
  • Production and characterization of monoclonal antibodies to human casein. A monoclonal antibody that cross-reacts with casein and alpha-lactalbumin.