Cat. #151524
Anti-Beta1 Connexin [2A]
Cat. #: 151524
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Connexin 32 (Cx32 or ?1)
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Chicken ; Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: David Becker
Institute: University College London (UCL)
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Beta1 Connexin [2A]
- Research fields: Cell signaling and signal transduction;Neurobiology
- Clone: 2A
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 46 kDa
- Reactivity: Chicken ; Human ; Mouse ; Rat
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Monoclonal antibody which detects connexin 32, linked to Charcot-Marie-Tooth disease.
- Immunogen: The peptide, LEGHGDPLHLEE, was coupled at the C-terminal end to bovine thyroglobulin at a final molar ratio peptide:thyroglobulin of 4060:1.
- Immunogen uniprot id: P08034
- Isotype: IgG
- Myeloma used: P3X63Ag8.653
- Recommended controls: Heart & liver tissue from 6 week old mice
Target Details
- Target: Connexin 32 (Cx32 or ?1)
- Molecular weight: 46 kDa
- Tissue cell line specificity: Mouse
- Target background: Connexins are a large family of proteins which form gap junctions. Gap junctions are cell membrane structures that facilitate direct cell-cell communication. Gap junctions are essential for various physiological processes, including coordinated depolarization of cardiac muscle, proper embryonic development, and the conducted response in microvasculature. Gap junction communication has been implicated in the patterning and development of vertebrate embryos. Individual connexins show complex sp...
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
References
- Wright et al. 2001. Reproduction. 121(1):77-88. PMID: 11226030.
- Stage-specific and differential expression of gap junctions in the mouse ovary: connexin-specific roles in follicular regulation.
