The atf1 gene of S. pombe encodes a bZIP transription factor with strong homology to the mammalian factor ATF2. This is regulated by the stress activated mitogen-activated protein kinases SAPK/JNK and p38.
| Inventor | Institute |
|---|---|
| Mike Samuels | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151204 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | WB ; ChIP ; IHC ; IP ; WB |
| Target: | Activating Transcription Factor 1 (ATF1) |
| Reactivity: | Human |
| Clone: | ATF1 2A9/8 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | The atf1 gene of S. pombe encodes a bZIP transription factor with strong homology to the mammalian factor ATF2. This is regulated by the stress activated mitogen-activated protein kinases SAPK/JNK and p38. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Yeast transcription factor ATF1 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | The atf1 gene of S. pombe encodes a bZIP transription factor with strong homology to the mammalian factor ATF2. This is regulated by the stress activated mitogen-activated protein kinases SAPK/JNK and p38. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Gmez-Gil et al. 2020. Elife. 9:. PMID: 32915139. Prieto-Ruiz et al. 2020. mBio. 11(1):. PMID: 31911490. Asada et al. 2017. Nucleic Acids Res. 45(16):9361-9371. PMID: 28934464. Wilkinson et al. 1996. Genes Dev. 10(18):2289-301. PMID: 8824588. The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. |
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