Cat. #151535
Anti-APC11 [AX2.1]
Cat. #: 151535
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Anaphase Promoting Complex (APC) 11
Class: Monoclonal
Application: ELISA ; WB
Reactivity: Human ; Xenopus laevis
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-APC11 [AX2.1]
- Research fields: Biochemistry;Cell biology
- Clone: AX2.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human ; Xenopus laevis
- Host: Mouse
- Application: ELISA ; WB
- Description: APC11 is the catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Specifically, Apc11 acts as an E3 enzyme and is responsible for recruiting E2s to the APC and for mediating the subsequent transfer of ubiquitin to APC substrates in vivo.
- Immunogen: Peptide spanning carboxy region of APC11.
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: APC11 immunoprecipitated from Xenopus egg extract
Target Details
- Target: Anaphase Promoting Complex (APC) 11
- Tissue cell line specificity: APC11 immunoprecipitated from Xenopus egg extract
- Target background: APC11 is the catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Specifically, Apc11 acts as an E3 enzyme and is responsible for recruiting E2s to the APC and for mediating the subsequent transfer of ubiquitin to APC substrates in vivo.
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
