#151280

Anti-AF10 [HAF10 9A5/2]

Cat. #151280

Anti-AF10 [HAF10 9A5/2]

Cat. #: 151280

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: AF10

Class: Monoclonal

Application: WB ; ELISA ; FACS ; IHC ; IP ; WB

Reactivity: Human ; Mouse

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Queen Mary University of London

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-AF10 [HAF10 9A5/2]
  • Research fields: Cancer;Genetics
  • Clone: HAF10 9A5/2
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: WB ; ELISA ; FACS ; IHC ; IP ; WB
  • Description: AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available.
  • Isotype: IgG2b
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: AF10
  • Target background: AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein.

Applications

  • Application: WB ; ELISA ; FACS ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • AF10 plays a key role in the survival of uncommitted hematopoietic cells.
  • Chamorro-Garcia et al. 2012. PLoS One. 7(12):e51626. PMID: 23284727.