Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody.
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| BioServ UK Ltd |
| Cat. #: | 153654 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Metabolism;Tissue-specific biology |
| Application: | ELISA |
| Target: | Adiponectin |
| Reactivity: | Human |
| Clone: | 399R |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Adiponectin, 3 kDa adipocyte complement-related protein, Adipocyte complement-related 3 kDa protein, ACRP3, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP3, APM1, GBP28 |
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| Product description: | Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (Hotta K, et al.) Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to the tail region of the Adiponectin molecule |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (Hotta K, et al.) Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Hazell, M.J. (2009) Development and Clinical Applications of Immunoassays for Human Adiponectin. Thesis. Oxford Brookes University Miller et al. 2011. Am J Physiol Endocrinol Metab. 301(4):E659-67. PMID: 21750269. Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Kiewiet et al. 2011. J Endocrinol Invest. 34(6):434-8. PMID: 20959720. Acute effects of acylated and unacylated ghrelin on total and high molecular weight adipone… |
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