Cat. #156513
pHBx-FLAG vector
Cat. #: 156513
Sub-type: pcDNA3.1
Availability: Please enquire for quantities and pricing
Target: HBx with FLAG tag at C-terminus
Bacterial Resistance: Ampicillin
Selectable Markers: Neomycin
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Michael Bouchard
Institute: Drexel University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: pHBx-FLAG vector
- Alternate name: nonstructural protein X, protein X, peptide X, pX
- Research fields: Cancer;Microbiology
- Tool sub type: pcDNA3.1
- Backbone size without insert: 5428
- Bacterial resistance: Ampicillin
- Selectable markers: Neomycin
- Description: This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells. The addition of the FLAG-epitope tag allows for detection in western and immunofluorescent cell-based studies and provides better detection ability than can currently be achieved with commercially available anti-HBx antibodies.
Handling
- Shipping conditions: Dry Ice
Target Details
- Target: HBx with FLAG tag at C-terminus
Application Details
- Application notes: Multi-functional hepatitis B viral protein, non-structural protein X, that modulates mitochondrial function in host hepatocytes interfering with host anti-viral defenses, promoting viral transcription, and contributing to hepatocellular carcinoma development.
References
- Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529.
- McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583.
