Cat. #155092
Anti-AvW-15 (von Willebrand Factor) [MBC 122.6]
Cat. #: 155092
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: von Willebrand Factor
Class: Monoclonal
Application: ELISA ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-AvW-15 (von Willebrand Factor) [MBC 122.6]
- Alternate name: vWf
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 250 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; WB
- Description: Von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
- Immunogen: R/A (reduced and alkylated) fragment of vWF (see notes column)
- Myeloma used: P3X63Ag8.653
- Recommended controls: IgG1
Target Details
- Target: von Willebrand Factor
- Molecular weight: 250 kDa
- Tissue cell line specificity: Mouse
- Target background: Von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Flood et al. 2018. Res Pract Thromb Haemost. 2(2):390-398. PMID: 30046743.
- Doruelo et al. 2017. J Thromb Haemost. 15(8):1559-1566. PMID: 28544236.
- Roberts et al. 2016. Blood. 127(20):2472-80. PMID: 26917779.
- Flood et al. 2015. Blood. 125(14):2297-304. PMID: 25662333.
- Flood et al. 2013. Clin Chem. 59(4):684-91. PMID: 23340442.
- Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572.
- Flood et al. 2011. Blood. 117(6):e67-74. PMID: 21148813.
