LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin.
| Institute |
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| University of Maryland |
| Cat. #: | 153993 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction;Genetics;Neurobiology |
| Application: | WB ; IF |
| Target: | Low density lipoprotein receptor-related protein-1, light chain |
| Reactivity: | Mouse ; Rat ; Human ; Rabbit |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | LRP1, Low density lipoprotein receptor-related protein 1, apolipoprotein E receptor (APOER), cluster of differentiation 91 (CD91), alpha-2-macroglobulin receptor (A2MR) |
|---|---|
| Product description: | LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 85/515/600 kDa |
| Target background: | LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Fnly, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. |
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| Format: | Liquid |
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| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775. Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multiFn receptor. |
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