Cat. #152599
Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
Cat. #: 152599
Sub-type: Primary antibody
Unit size: 100 ug
Target: Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase
Class: Monoclonal
Application: IHC ; WB ; ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: V29-P4B8*B2
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB ; ELISA ; IHC ; WB
- Description: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
- Immunogen: Ovalbumin-conjugated synthetic peptide KVVLAPETGEL (C-terminal sequence)
- Isotype: IgG1 kappa
- Recommended controls: IHC: formalin-fixed, paraffin-embedded human sections; WB: Overexpression lysates
Target Details
- Target: Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase
- Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded human sections; WB: Overexpression lysates
- Target background: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Applications
- Application: IHC ; WB ; ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20° C
- Shipping conditions: Shipping at 4° C
References
- Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- Swan et al. 2016. Oncotarget. :. PMID: 27341022.
