The 4E9 antibody binds to the mouse C57 NKRP1D (CD161b/d) receptor with very low cross reactivity on NKRP1A, NKRP1C, and possibly NKRP1F transfectant
| Inventor | Institute |
|---|---|
| Colin Brooks | Newcastle University |
| Cat. #: | 151815 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | Fn |
| Target: | NKRP1D |
| Reactivity: | Mouse |
| Clone: | 4.00E+09 |
| Host: | Rat |
| Class: | Monoclonal |
| Alternate name: | Killer Cell Lectin Like Receptor B1; Natural Killer Cell Surface Protein P1A; C-Type Lectin Domain Family 5 Member B; HNKR-P1A; CLEC5B; NKRP1A; CD161 Antigen; NKR |
|---|---|
| Product description: | The 4E9 antibody binds to the mouse C57 NKRP1D (CD161b/d) receptor with very low cross reactivity on NKRP1A, NKRP1C, and possibly NKRP1F transfectants. It may bind to NKRP1 molecules in other strains but this has not been investigated in detail. Note that this mAb shows weaker staining than the 2D9 NKRP1D mAb (Cat #151814), but has higher activity in functional assays. |
| Conjugation: | Unconjugated |
| Isotype: | IgG3 kappa |
| Immunogen: | YB2/0 rat plasmacytoma cells transfected with NKRP1 |
| Myeloma used: | NS0 |
| Target background: | The 4E9 antibody binds to the mouse C57 NKRP1D (CD161b/d) receptor with very low cross reactivity on NKRP1A, NKRP1C, and possibly NKRP1F transfectants. It may bind to NKRP1 molecules in other strains but this has not been investigated in detail. Note that this mAb shows weaker staining than the 2D9 NKRP1D mAb (Cat #151814), but has higher activity in functional assays. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1mg/ml |
| Storage buffer: | DMEM, 5 x10 5 M 2 ME, and 10% FBS |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Aust et al., 2009. J. Immunol. 183:106-16. PMID: 19535641 |
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