Anti-LSP1 [TPD153]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-LSP1 [TPD153]
• Research fields: Cell signaling and signal transduction;Immunology
• Clone: TPD153
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Reactivity: Human
• Host: Mouse
• Application: IHC ; IP ; WB
• Description: Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII).
• Immunogen: Tonsil cells
• Isotype: IgG1 kappa
• Myeloma used: P3/NS1/1-Ag4.1

Target Details

• Target: Lymphocyte Specific Protein-1 (LSP1)
• Target background: Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII).

Applications

• Application: IHC ; IP ; WB

Handling

• Format: Liquid
• Concentration: 1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Marafioti et al. 2004. Haematologica. 89(8):957-64. PMID: 15339679.
• Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease.
• Marafioti et al. 2003. Br J Haematol. 120(4):671-8. PMID: 12588355.
• Leucocyte-specific protein (LSP1) in malignant lymphoma and Hodgkin's disease.
• Pulford et al. 1999. Immunology. 96(2):262-71. PMID: 10233704.
• Lymphocyte-specific protein 1: a specific marker of human leucocytes.