Cat. #154337

pTRE/SP M1 N184X vector

Cat. #: 154337

Sub-type: pTRE-Tight

Availability: Please enquire for quantities and pricing

Target: spastin

Bacterial Resistance: Ampicillin

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

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Contributor

Institute: Drexel University

Tool Details

Target Details

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Tool name: pTRE/SP M1 N184X vector
Research fields: Cell biology;Genetics;Neurobiology
Tool sub type: pTRE-Tight
Backbone size without insert: 2600
Bacterial resistance: Ampicillin
Description: Plasmids for the study of hereditary spastic paraplegia
Additional notes: Plasmids for the study of hereditary spastic paraplegia

Target Details

Target: spastin

References

Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.
Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.