pTRE/SP C448Y w/ 5’UTR vector

Plasmids for the study of hereditary spastic paraplegia

Contributors

Institute
Drexel University
Cat. #: 154343
Tool sub type: pTRE-Tight
Research Fields: Cell biology;Genetics;Neurobiology
Target: spastin
Backbone size without insert: 2600
Bacterial resistance: Ampicillin
Product description: Plasmids for the study of hereditary spastic paraplegia
Additional notes: Plasmids for the study of hereditary spastic paraplegia
References:

Solowska et al. 2014. J Neurosci. 34(5):1856-67. PMID: 24478365.

Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.

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