| Institute |
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| Drexel University |
| SKU: | 154130 |
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| Product description: | This plasmid is useful for testing the the transactivation activity of HIF-1a |
| Additional notes: | This plasmid is useful for testing the the transactivation activity of HIF-1a |
| Cat. #: | 154130 |
|---|---|
| Tool sub type: | pM |
| Research Fields: | Genetics; Metabolism |
| Target: | HIF-1a (Truncated) and GAL4 (DNA binding domain) |
| Backbone size without insert: | 3500 |
| Bacterial resistance: | Ampicillin |
| Selectable markers: | Ampicillin, G418 |
| References: |
Sang et al. 2003. J Biol Chem. 278(16):14013-9. PMID: 12588875. MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. Sang et al. 2002. Mol Cell Biol. 22(9):2984-92. PMID: 11940656. Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP. |
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