OV-90 Cell Line

Ascites-derived serous ovarian cancer cell line established before chemotherapy, suitable for studies of serous ovarian cancer biology and ascites-associated tumour behaviour

Contributors

Inventor Institute
Anne-Marie Mes-Masson and Diane Provencher Centre Hospitalier de L'universite de Montreal
SKU: 161765
Product description: OV-90 is an epithelial ovarian cancer cell line derived from the cellular fraction of malignant ascites collected from a chemotherapy-naïve patient with serous ovarian cancer. The model has been extensively characterised and has been used to study ovarian cancer cell invasion, growth, spheroid formation and responses to factors present in malignant ascites. Its serous histology and ascites origin make OV-90 particularly useful for investigating tumour behaviour within an ascites-associated environment and for testing whether findings extend across different ovarian cancer histotypes and sample sources.
Alternate name: OV-90
Gender: Female
CRISPR: No
Cellosaurus ID: CVCL_3768
Receptors of note: No
Related tools: 161764 ; 161766
Cat. #: 161765
Cancer types: Ovarian cancer
Research Fields: Cancer
Organism: Human
Tissue: Derived from malignant ascites of a chemonaive ovarian cancer patient
Gender: Female
Primary citation: Provencher et al. 2000. In Vitro Cell Dev Biol Anim. (36): 357–361. PMID:10949993.
Shipping conditions: Dry Ice
References:

Raspaglio et al. 2023. Cancers (Basel). 18

15(8):2361. PMID: 37190289 Yee et al. 2022. Front Bioeng Biotechnol. 10

10:836984. PMID: 35223797 Brodeur et al. 2021. Sci Rep. 14

11(1):18183. PMID: 34521878 Buttarelli et al. 2022. J Exp Clin Cancer Res. 4

41(1):50. PMID: 35120576

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