| Inventor | Institute |
|---|---|
| Anne-Marie Mes-Masson and Diane Provencher | Centre Hospitalier de Luniversité de Montréal |
| SKU: | 161771 |
|---|---|
| Product description: | Epithelial ovarian cancer cell line derived from matched ascites from TOV-1946. Cell line derived from ascites of chemotherapy naive patient who presented poorly differentiated (grade 3) serous papillary cystadenocarcinoma at stage IIC |
| Alternate name: | OV-1946 |
| Gender: | Female |
| CRISPR: | No |
| Production details: | Established from a mass of cells from ascites of patient 1946. Mass was macro-dissected and kept in 100mm petri dish for 27 days where they reached 80% confluence. Tissue was discarded and cells were divided 2:3 every week for the first 15 passages and 1:2 twice a week until passage 70. Cells were mantianed and divided 1:5 twice a week afterwards |
| Additional notes: | Patient 1946 had no known familial history of cancer and passed from post-operative complications |
| Cellosaurus ID: | CVCL_4375 |
| Receptors of note: | No |
| Cat. #: | 161771 |
|---|---|
| Cancer types: | Ovarian cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Tissue: | Derived from matched ascites from case TOV-1946 |
| Gender: | Female |
| Morphology: | Able to form less compact spheroids and expressed Krt7 |
| Growth properties: | Adherent |
| Primary citation: | Ouellet et al. 2008. BMC Cancer. (8):152. PMID: 18507861 |
| Shipping conditions: | Dry Ice |
|---|---|
| Growth medium: | OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin |
| Atmosphere: | Hypoxic condition of 5%O2 and 5%CO2 |
| References: |
Sauriol et al. 2023. Sci Rep. 27 13(1):3334. PMID: 36849518 Sevinyan et al. 2022. Cancers (Basel). 16 14(22):5628. PMID: 36428724 Brodeur et al. 2021. Sci Rep. 14 11(1):18183. PMID: 34521878 Communal et al. 2021. Int J Mol Sci. 18 22(10):5325. PMID: 34070214 Patra et al. 2020 PLoS One. 31 15(12):e0244549. PMID: 33382759 |
|---|
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