CHO DC-SIGN WT is a Chinese hamster ovary cell line expressing wild-type DC-SIGN/CD209, a C-type lectin receptor involved in pathogen recognition and ligand binding. It provides a cell-based model for studying DC-SIGN-mediated interactions with microbial and viral ligands, including pathogens such as HIV-1, Ebola virus, hepatitis C virus, Mycobacterium tuberculosis and Candida albicans. It is suitable for studies of receptor–ligand binding, pathogen recognition and C-type lectin receptor biology.
Alternate name:
DC-SIGN
Conditional:
No
Production details:
CHO cell lines stably expressing DC-SIGN wild-type were established by Lipofectamin 2000 transfection, and were cultured in HamÄË?Â?Âs F-12 medium supplemented with 10% heat-inactivated FBS, 1% Antibiotic Antimycotic Solution , and 0.5ÄË?Â?Âmg/ml of the aminoglycoside antibiotic G418.
Parental cell line:
CHO
Disease:
HIV-1
Cat. #:
160716
Unit size:
1×10^6 cells / vial
Research Fields:
Cell signaling and signal transduction; Immunology
Organism:
Hamster
Tissue:
Ovary
Format:
Frozen
Shipping conditions:
Dry ice
Growth medium:
HamÄË?Â?Âs F-12 medium supplemented with 10% heat-inactivated FBS, 1% Antibiotic Antimycotic Solution , and 0.5ÄË?Â?Âmg/ml of the aminoglycoside antibiotic G418.
Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.
