Antibody for WD Repeat-Containing Protein 12 (WDR12), a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including […]
| Institute |
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| Helmholtz Munich Core Facility Monoclonal Antibodies |
| Cat. #: | 162383 |
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| Tool sub type: | Primary antibody |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | WB |
| Target: | WD-repeat 12 (WDR12) |
| Reactivity: | Human |
| Clone: | WDR12 1B8 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Holzel et al. 2005. J. Cell Biol. 170: 367-378. PMID: 16043514 |
| Alternate name: | Anti WD-repeat 12 (WDR12) monoclonal antibody (clone WDR12 1B8) |
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| Product description: | Antibody for WD Repeat-Containing Protein 12 (WDR12), a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR12 has been implicated in liver cancer. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | GST-WDR12 fusion protein |
| Target background: | WD Repeat-Containing Protein 12 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR12 has been implicated in liver cancer. |
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| References: |
Holzel et al. 2005. J. Cell Biol. 170: 367-378. PMID: 16043514 |
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