Anti-SNF2H [SNF2H]

SNF2H is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins.

Contributors

Inventor Institute
Patrick Varga-Weisz Marie Curie Research Institute
Cat. #: 151584
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Genetics
Application: ChIP ; IHC ; IF ; IP ; WB
Target: SNF2H
Reactivity: Human ; Mouse
Clone: SNF2H
Host: Rabbit
Class: Polyclonal
Product description: SNF2H is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins. The members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SNF2H is the catalytic subunit of several chromatin remodelling complexes, such as CHRAC, RSF, ACF, NuRD and NoRC. SNF2H is similar in sequence to the Drosophila ISWI chromatin remodelling protein.
Conjugation: Unconjugated
Molecular weight: 121 kDa
Immunogen: Peptide coupled to keyhole limpet hemocyanin
Target background: SNF2H is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins. The members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SNF2H is the catalytic subunit of several chromatin remodelling complexes, such as CHRAC, RSF, ACF, NuRD and NoRC. SNF2H is similar in sequence to the Drosophila ISWI chromatin remodelling protein.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: Whole serum
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Mueller et al. 2013. Oncogene. 32(9):1164-72. PMID: 22525276.

The miR-99 family regulates the DNA damage response through its target SNF2H.

Sacilotto et al. 2011. PLoS One. 6(8):e23318. PMID: 21858068.

Epigenetic transcriptional regulation of the growth arrest-specific gene 1 (Gas1) in hepatic cell proliferation at mononucleosomal resolution.

Lessard et al. 2010. Mol Cell. 38(4):539-50. PMID: 20513429.

The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I.

Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.

WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.

Images

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Adapted from Sacilotto et al. 2011. PLoS One. 6(8)

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