Anti-Myelin Basic Protein (region 82-87) [MBP12]
MBP Clone 12 recognizes an epitope in the 82-87 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
Contributors
| Institute |
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| BioServ UK Ltd |
| SKU: | 153641 |
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| Product description: | Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 12 recognizes an epitope in the 82-87 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP. MBP 12 is also used in a two-site ELISA with clone MBP 40. Both are used interchangeably as capture and detection antibody. |
| Alternate name: | Myelin basic protein, MBP, 2 kDa microtubule-stabilizing protein, Myelin A1 protein |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 13-21 kDa |
| Immunogen: | Reacts with human MBP, recognizing epitopes in the 82-87 amino acid region (DENPVV) |
| Myeloma used: | NS0 |
| Cat. #: | 153641 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Cancer types: | Brain cancer |
| Research Fields: | Cell biology; Immunology; Neurobiology; Stem cell biology |
| Application: | FACS ; ELISA ; IHC ; IF ; WB |
| Target: | Myelin Basic Protein (region 82-87) |
| Reactivity: | Chicken ; Human ; Guinea Pig ; Pig ; Rat ; Rabbit ; Sheep ; Mammals |
| Clone: | MBP12 |
| Host: | Rat |
| Class: | Monoclonal |
| Target background: | Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 12 recognizes an epitope in the 82-87 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP. MBP 12 is also used in a two-site ELISA with clone MBP 40. Both are used interchangeably as capture and detection antibody. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Grigoletto et al. 2017. Acta Neuropathol Commun. 5(1):37. PMID: 28482862. Higher levels of myelin phospholipids in brains of neuronal a-Synuclein transgenic mice precede myelin loss. Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499. Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499. Fernandes et al. 2016. J Control Release. 238:300-310. PMID: 27369863. Isoda et al. 2016. Neurosci Res. 110:18-28. PMID: 27083781. Lim et al. 2016. Antioxidants (Basel). 5(… |
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Clone 12 used to detect MBP in myelinating cell cultures using Immunofluorescence. Time-lapse imaging of the putative assembly of myelin membrane. B) The cells from the Petri dish imaged with confocal microscopy were immunostained with anti-GFP and anti-MBP to confirm differentiation of cyto-GFP labelled oligodendrocytes. Source
Related Tools for Antibodies
| Cat. # | Tool Name | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 153643 | Anti-Myelin Basic Protein [MBP40] |
Key Info
Anti-Myelin Basic Protein [MBP40]
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