Anti-LewisX [28]

Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.

Contributors

Inventor Institute
Nancy Hogg Cancer Research UK, London Research Institute: Lincoln's Inn Fields
SKU: 151041
Product description: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
Alternate name: Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
Conjugation: Unconjugated
Isotype: IgM
Molecular weight: 83 kDa
Immunogen: Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates.
Myeloma used: Sp2/0-Ag14
Cat. #: 151041
Provenance and Ownership: The Anti-LewisX 28 is owned by Cancer Research UK. CancerTools supplies the Anti-LewisX 28 under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-LewisX 28 directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer; Immunology
Application: IHC ; IP ; FACS ; IHC ; IP
Target: Lewis X (CD15)
Reactivity: Human
Clone: 28
Host: Mouse
Class: Monoclonal
Primary citation: Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
Target background: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
Format: Liquid
Concentration: 0.71 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -80° C
Shipping conditions: Dry ice
References:

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.

Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.

Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML.

Images

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Adapted from Hogg et al. 1984. Immunology. 53(4)

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