X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| SKU: | 151346 |
|---|---|
| Product description: | Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts. |
| Alternate name: | CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; CD8 Antigen; Alpha Polypeptide (P32); MAL; T-Cell Surface Glycoprotein CD8 Alpha Chain; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2; T8 T-Cell Antigen; CD8a Antigen; Leu2; P32 |
| Conjugation: | Unconjugated |
| Isotype: | Not Known |
| Immunogen: | Synthetic peptide ( the 13 c-terminal residues of the cytoplasmic domain of human CD8a) |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151346 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology;Stem cell biology |
| Application: | FACS ; IHC |
| Target: | Leu2 (CD8) |
| Reactivity: | Human |
| Clone: | X107 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672 |
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