Anti-IL21 [V28P5G1*C4]

IL21 is a member of the type I cytokine family, which includes IL2 and IL15. IL21 signals through the common gamma-chain and a unique IL21 receptor. The IL21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL21 is a key component of CD4 […]

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
Cat. #: 153375
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Immunology
Application: ELISA ; IHC ; WB
Target: Interleukin 21 (IL21)
Reactivity: Salmon ; Rainbow Trout
Clone: V28P5G1*C4
Host: Mouse
Class: Monoclonal
Alternate name: IL 21 antibody, Interleukin 21 antibody, Interleukin21 antibody
Product description: IL21 is a member of the type I cytokine family, which includes IL2 and IL15. IL21 signals through the common gamma-chain and a unique IL21 receptor. The IL21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.
Conjugation: Unconjugated
Isotype: IgG
Immunogen: Ovalbumin-conjugated synthetic peptide- LLQKAISRLA
Myeloma used: P3X63Ag8.653
Target background: IL21 is a member of the type I cytokine family, which includes IL2 and IL15. IL21 signals through the common gamma-chain and a unique IL21 receptor. The IL21 receptor is expressed in cells lymphoid-lineage and regulates the proliferation and differentiation of T and B lymphocytes. Studies suggest that IL21 is a key component of CD4 T cell help that is required for maintaining the CD8+ T cell responses and inducing B cell antibody response. IL21 also promotes the development of Th17 and Tfh cells, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. It is also implicated in the development of autoimmune disease and has antitumor activity.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

Images

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Western blot data shows Anti-IL21 [V28P5G1*C4] specifically recognizes recombinant IL21 (expected size 20 KDa)

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