ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses.
| Institute |
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| University of Birmingham |
| SKU: | 151489 |
|---|---|
| Product description: | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. |
| Alternate name: | Intercellular Adhesion Molecule 3; ICAM-3; ICAM-R; CDW5; CD5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151489 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology; Cell signaling and signal transduction; Immunology |
| Application: | FACS ; IP |
| Target: | ICAM3 (CD50) |
| Reactivity: | Human |
| Clone: | BU65 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Mason DY. Leucocyte Typing VII. 2002. OUP, Oxford. |
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