Anti-HuR [4C8] (ChIP Grade)

SKU: 153520
Product description: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.
Alternate name: ELAV-like protein 1, Human antigen R
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: HuR peptide
Cat. #: 153520
Unit size: 100 ug
Research Fields: Genetics
Application: ChIP ; ELISA ; IHC ; EMSA
Target: HuR
Reactivity: Human
Clone: 4C8
Host: Mouse
Class: Monoclonal
Target background: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.
Format: Liquid
Shipping conditions: Dry ice

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