Anti-HSP90 alpha/beta [MBH90AB]

An Anti-HSP90 alpha/beta mouse monoclonal antibody

Contributors

Institute
Moravian Biotechnology
SKU: 162061
Product description: Antibody created to detect Hsp90a and Hsp90b proteins. Binding specificity: proteins Hsp90a and Hsp90b, calculated epitope KEFEGKT.
Conjugation: Unconjugated
Isotype: IgG1
Molecular weight: Calculated: 84660Da (Hsp90?), 83264Da (Hsp90?); SDS-PAGE mobility (reduced): 90kDa for both Hsp90? and Hsp90?
Immunogen: human Hsp90?
Cat. #: 162061
Tool sub type: Primary antibody
Target: alpha/beta forms of heat shock protein 90 (HSP90 alpha/beta)
Reactivity: Human ; mouse ; bovine
Clone: MBH90AB
Host: Mouse
Class: Monoclonal
Target background: Hsp90 is involved in maintaining the conformation, stability, activity and localization of several client proteins that trigger key points of oncogenic transformation (like mutant p53, steroid hormone receptors, HER2/neu, C-RAF, CDK4/Cyclin D, telomerase hTERT, etc.). Therefore, modulation of this single target offers the prospect of simultaneous inhibition of multiple signaling pathways and biological processes that might be implicated in the development of the malignant phenotype.
Format: Liquid
Shipping conditions: Dry ice

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