EHop-016 Rac1 Inhibitor

EHop-016 Rac1 Inhibitor is a novel small molecule directed at metastatic breast cancer. Potent Rac inhibitor reporting the identification and characterization of the biological activity of EHop-016, a novel NSC23766 derivative that inhibits Rac1 100-fold more effectively than the parent compound.

Contributors

Inventor Institute
Suranganie Dharmawardhane University of Puerto Rico
Cat. #: 161689
Research Fields: Cancer
Application: Further development as a pharacological inhibitor of Rac activity in metastatic cancer cells
Purpose: Designed to be a more potent Rac Inhibitor with possible clinical applications
Primary citation: Montalvo-Ortiz et al. J Biol Chem. 287(16): 13228-13238. PMID: 22383527
Product description: EHop-016 Rac1 Inhibitor is a novel small molecule directed at metastatic breast cancer. Potent Rac inhibitor reporting the identification and characterization of the biological activity of EHop-016, a novel NSC23766 derivative that inhibits Rac1 100-fold more effectively than the parent compound.
Primary target: Rac
References:

Montalvo-Ortiz et al. J Biol Chem. 287(16): 13228-13238. PMID: 22383527

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