AKR1C3 inhibitor CRT0093964 Small Molecule (Tool Compound)

CRT0093964 is a highly potent and selective inhibitor of the Type 5 17-?-Hydroxysteroid Dehydrogenase (AKR1C3).

Contributors

Inventor Institute
Laurent Rigoreau Cancer Research Technology
Cat. #: 151880
Tool sub type: Inhibitor
Research Fields: Cell signaling and signal transduction;Metabolism;Neurobiology
Purpose: Inhibitor
Product description: CRT0093964 is a highly potent and selective inhibitor of the Type 5 17-?-Hydroxysteroid Dehydrogenase (AKR1C3).
Additional notes: Referred to as A9 in Khanim et al., 2014.
Molecular weight: 309.79
Selectivity: Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4. Does not display any COX (cyclooxygenase) inhibition at 10 ÂľM in whole blood assay.
Primary target: Type 5 17-?-Hydroxysteroid Dehydrogenase (AKR1C3)
Shipping conditions: Dry Ice
References:

Khanim et al. 2014. Br J Cancer. 110(6):1506-16. PMID: 24569460.

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