PL2 Peptide

The PL2 specific peptide has enhanced affinity to bind to FN-EDB. It has previously been used as a target for antibody-based therapies.

Contributors

Inventor Institute
Prakash Lingasamy ; Tambet Teesalu University of Tartu
Cat. #: 157665
Tool sub type: Synthetic Peptide
Research Fields: Cancer;Cell biology
Alternate name: PL2, Oncofetal fibronectin (FN-EDB) specific peptide
Product description: Oncofetal fibronectin (FN-EDB) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. The PL2 specific peptide has enhanced affinity to bind to FN-EDB so may be useful as an affinity ligand for delivery of diagnostic compounds into solid tumours.
Function: Marker
Expression system: Synthetic

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