PL1 peptide

This dual-targeted peptide can be used for robust and specific delivery of imaging agents and therapeutic payloads to solid tumours.

Contributors

Inventor Institute
Tambet Teesalu ; Prakash Lingasamy University of Tartu
Cat. #: 158320
Tool sub type: Synthetic Peptide
Research Fields: Cancer;Cell biology
Alternate name: PL1, FN-EDB and TNC-C binding protein
Product description: PL1 peptide is a short binding peptide which interacts with oncofetal fibronectin extra domain-B (FN-EDB) and tenascin-C C domain (TNC-C) which are both extracellular matrix proteins present in a tumour microenvironment. The targets of PL1 are nearly absent in normal adult tissues making them indicative of solid tumour tissues. It has been shown that this dual-targeted peptide can be used for robust and specific delivery of imaging agents and therapeutic payloads to solid tumours.
Function: Marker
Expression system: Synthetic
References:

Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery

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