NF712 peptide

this peptide has been developed to improve the efficiency of nucleic acid delivery

Contributors

Inventor Institute
Piret Arukuusk ; Ly Porosk ; Ülo Langel University of Tartu
Cat. #: 157649
Tool sub type: Synthetic Peptide
Research Fields: Genetics
Alternate name: NickFect712
Product description: This peptide can be used to transport siRNA into cells. Use of cell-penetration peptides can increase the transport efficiency of extracellular synthetic nucleic acids, such as siRNAs, to help increase concentration of the siRNA at the desired cellular location. This peptide is based on NickFect55 (NF55) which is a peptide that can efficiently transport plasmid DNA into cells in vivo. To improve the efficiency of nucleic acid delivery, this peptide has been developed to improve the intracellular release mechanism resulting in higher local dosage of the cargo.
Additional notes: There is an arachidyl (20-carbon) fatty acid chain attached to the N-terminus of the peptide. The sequence in brackets is attached to the sidechain amino group rather than the a-amino group.
Function: siRNA delivery
Tag: arachidyl (20-carbon) fatty acid chain attached to the N-terminus of the peptide
Expression system: Synthetic
References:

Porosk et al. 2019. Biomater Sci. 7(10):4363-4374. PMID: 31411219.

Related Tools for Proteins

Cat. # Tool Name
151860 Integrin AvB6 inhibiting Peptide Key Info View Tool
153542 Endo-Beta-N-acetylglucosaminidase (Endo Tv), Enzyme Key Info View Tool
153953 Lichenase A Key Info View Tool
156503 p65-glutathione S-transferase (GST) fusion Protein Key Info View Tool
157664 PL5 Peptide Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.